Tyrann Mathieu Grabs the 2nd Pick Six of the 1st Quarter | Cardinals vs. 49ers | NFL

Tyrann Mathieu Pick 6!See more

Tyrann Mathieu Gets a Pick 6 in the First Minute!See more

Tyrann Mathieu’s SAVAGE TRASH TALK Mic’d Up 😳🍿 #nfl #shortsSee more

Tyrann Mathieu w/ the Easy Pick 6!See more

Tyrann Mathieu Pick 6 After Julian Edelman Drop | NFL Week 4See more

2017 Patriots.. 😢See more

Tyrann Mathieu Picks Off Blaine Gabbert! | Cardinals vs. 49ers | NFLSee more

Antonio brown before, and after the hit.See more

Honey Badger Don't Care! Tyrann Mathieu Takes Down Peterson! | Vikings vs. Cardinals | NFLSee more

Arizona Cardinals vs. San Francisco 49ers Full Highlights 1st QTR | NFL Week 4, 2023See more

Tyrann Mathieu Pick SIX!See more

Mac Jones Throws PICK SIX to Tyrann Mathieu | Patriots vs SaintsSee more

Tyrann Mathieu PICK 6 to open the gameSee more

Tyrann Mathieu Pick 6 | Pats vs. Chiefs | NFLSee more

Tyrann Mathiue INTSee more